Quote
K. Xiao, A. S. Thalmayer, J. Kirchner, and G. Fischer, “Physics of SPION–Surface Interactions in Fluidic Channels: Implications for Molecular Communication Systems,” IEEE Transactions on Molecular, Biological, and Multi-Scale Communications, vol. 12, pp. 504–509, 2026, doi: 10.1109/tmbmc.2026.3686303
Content
It is promising to study magnetic drug targeting using molecular communication (MC) frameworks, which model superparamagnetic iron oxide nanoparticles (SPIONs) as nanoscale information carriers. However, a key factor influencing MC performance—the physics governing SPION adhesion to channel surfaces—remains poorly characterized. This study establishes a computational model of SPION dynamics to elucidate the adhesion mechanisms. Our results reveal that the relative balance between van der Waals forces and electrostatic forces is the primary factor determining SPION adhesion behavior. Furthermore, we determined the relationship between this balance and the ion concentration of the medium. Based on these insights, we propose strategies to reduce adhesion and thereby improve the performance of MC systems.
References and Relationships
DOI 10.1109/tmbmc.2026.3686303
OpenAlex ID W7155099765